Women with TSC: Relationship between Clinical, Lung Function and Radiological Features in a Genotyped Population Investigated for Lymphangioleiomyomatosis
(Per leggere l’articolo clicca QUI)
Fabiano Di Marco, Silvia Terraneo, Gianluca Imeri, Giuseppina Palumbo, Francesca La Briola, Silvia Tresoldi, Angela Volpi, Lorenzo Gualandri, Filippo Ghelma, Rosa Maria Alfano, Emanuele Montanari, Alfredo Gorio, Elena Lesma, Angela Peron, Maria Paola Canevini, Stefano Centanni
PLOSE ONE, May 12, 2016

Anti-EGFR Antibody Reduces Lung Nodules by Inhibition of EGFR-Pathway in a Model of Lymphangioleiomyomatosis
(Per leggere l’articolo clicca QUI)
Elena Lesma, Eloisa Chiaramonte, Silvia Ancona, Emanuela Orpianesi, Anna Maria Di Giulio, and Alfredo Gorio
Hindawi Publishing Corporation BioMed Research International Volume 2015

TSC epigenetic defect in primary LAM cells. Evidence of an anchorage-indipendent survival.
(Per leggere l’articolo clicca QUI)
Elena Lesma, Silvia Ancona, Silvia M. Sirchia, Emanuela Orpianesi, Vera Grande, Patrizia Colapietro, Eloisa Chiaramonte, Anna Maria Di Giulio, Alfredo Gorio
J. Cell. Mol. Med. Vol 18, No 5, 2014 pp 766-779

Chromatin remodelling by rosuvastatin normalizes TSC2-/meth cell phenotype through the expression of tuberin.
(Per leggere l’articolo clicca QUI)
Lesma E., Ancona S., Orpianesi E., Grande V., Di Giulio AM., Gorio A.
J Pharmacol Exp Ther 2013; 345:180–188

Development of a Lymphangioleiomyomatosis model by endonasal administration of human TSC2-/- smooth muscle cells in mice.
(Per leggere l’articolo clicca QUI)
Lesma E., Chiaramonte E., Isaia E., Grande V., Ancona S., Orpianesi E., Di Giulio A.M., Gorio A.
Am J Pathol 181(3) : 947-960 (2012)

Lymphangioleiomyomatosis and TSC2-/- Cells.
Thomas N. Darling, Gustavo Pacheco-Rodriguez, Alfredo Gorio, Elena Lesma, Cheryl Walker, Joel Moss.
Articolo pubblicato su LYMPHATIC RESEARCH AND BIOLOGY. Febbraio 2010.

LRB 2009

Development of a Lymphangioleiomyomatosis model by endonasal administration of human TSC2-/- smooth muscle cells in mice.
(Per leggere l’articolo clicca QUI)
Lesma E., Chiaramonte E., Isaia E., Grande V., Ancona S., Orpianesi E., Di Giulio A.M., Gorio A.
Am J Pathol 181(3) : 947-960 (2012)

Am J Pathol 2009

Articoli pubblicati nel sito dell’Azienda Ospedaliera San Paolo di Milano – Polo Universitario:

Prestigioso premio (ATS/LAM Foundation Award 2009) riconosciuto alla dott.ssa Elena Lesma.
Aprile 2009
Articolo pubblicato su ATS (America Thoracic Society) News.
Vedi a pag. 9 (3,12 Mb)

ATS News 2009

Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2 -/- Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and LAM.
(Per leggere l’articolo clicca QUI)
Elena Lesma, Vera Grande, Silvia Ancona, Stephana Carelli, Anna Maria Di Giulio, Alfredo Gorio.
Articolo pubblicato su PLoS ONE. Ottobre 2008.

PLOS ONE 2008

Isolation and growth of smooth muscle-like cells derived from tuberous sclerosis complex-2 human renal angiomyolipoma: epidermal growth factor is the required growth factor.
Lesma E, Grande V, Carelli S, Brancaccio D, Canevini MP, Alfano RM, Coggi G, Di Giulio AM, Gorio A.
Am J Pathol. 2005 Oct; 167(4):1093-103.